Transporter Scientist Within The Ddi Section In The Department Of Drug Metabolism

Bio Engineering
H Lundbeck A S
Your job: You will be responsible for implementing drug transporter studies within the DDI section and in particular setting up new assays/cell cultures in the laboratory. Furthermore, we expect you to be or become our drug transporter specialist. In addition to the transporter studies, you will be responsible for planning, executing and reporting of other in vitro DDI metabolism studies including enzyme reaction phenotyping, enzyme inhibition and enzyme induction. The data obtained will be used for simulation of PK and DDI using SimCYP. Thus you will also be involved in SimCYP simulations. Furthermore, you will also be involved in studies to elucidate the mechanism behind a given observation. The techniques primarily used are LC-MS-MS and radiochemical detection. Another part of your work will be close collaboration with Contract Research Organisations (CRO’s), who are performing studies on behalf of the DDI section. As a scientist you will also be involved in project teams, representing the department or the non-clinical Safety Research area. The primary responsibility of the project team member is to drive the project forward and carry out decisions made by the team.
Kopenhagen
Your Qualifications: This pivotal role within Lundbeck requires the proven experience of a highly experienced scientist whose attributes include the following parameters: PhD in biochemistry, pharmacy, chemical engineering or equivalent. A solid understanding of and interest in biochemistry in general. A solid understanding of and experience with drug transporters in the laboratory Experience with cell-based assays and enzyme assays Experience with LC-MS techniques and radiochemical-detection (14C). Knowledge within SimCYP Knowledge of genetic polymorphism Experience in preparing protocols and reports Enthusiastic, proactive and a true team player Good communication skills and fluent in English.
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Transporter Scientist Within The Ddi Section In The Department Of Drug Metabolism
Bio Engineering
Your job: You will be responsible for implementing drug transporter studies within the DDI section and in particular setting up new assays/cell cultures in the laboratory. Furthermore, we expect you to be or become our drug transporter specialist. In addition to the transporter studies, you will be responsible for planning, executing and reporting of other in vitro DDI metabolism studies including enzyme reaction phenotyping, enzyme inhibition and enzyme induction. The data obtained will be used for simulation of PK and DDI using SimCYP. Thus you will also be involved in SimCYP simulations. Furthermore, you will also be involved in studies to elucidate the mechanism behind a given observation. The techniques primarily used are LC-MS-MS and radiochemical detection. Another part of your work will be close collaboration with Contract Research Organisations (CRO’s), who are performing studies on behalf of the DDI section. As a scientist you will also be involved in project teams, representing the department or the non-clinical Safety Research area. The primary responsibility of the project team member is to drive the project forward and carry out decisions made by the team.

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Senior Scientist In Chemistry
ResearchandDevelopment
Department SABIC’s Technology and Innovation (T&I) network consists of more than 1500 employees across 6 research- and 10 application centers around the world. The T&I organisation supports SABIC’s global businesses in realising its objectives by providing Best-In-Class Technology solutions. In Europe, the SABIC Technology Center (STC) is based in Geleen (The Netherlands) and Wilton, UK. The primary activity of STC Geleen is to define and to work out research projects aimed at the optimization of existing petrochemical processes and products and development of new ones. Our Chemistry and Catalysis Development department has team members from Geleen and Wilton locations. The Challenge As a Lead or Staff Scientist you will be working in a very professional Technology & Innovation organization. Your tasks and responsibilities include: To work out options to improve the production process and product performance in terms of quality, consistency and costs; To work in a multidisciplinary setting, both within Technology & Innovation (T&I disciplines) and in the business environment (business disciplines); To work closely with colleagues in SABIC Manufacturing to help optimise plant operation, understand the causes of fouling, catalyst failure or any liquid cracking chemistry related problems and identify workable process improvement opportunities; To co-ordinate tasks by effectively defining goals and priorities and identifying activities and resources needed to achieve these goals. Your Profile You are educated to a PhD level (Technical University: focus on physical /organic /industrial chemistry) and several years of related work experience (min 5) in organic & applied chemistry on an industrial scale. Your experience preferably in liquid cracking chemistry or Fouling area. You are able to utilize this knowledge into a petrochemical industry setting. You are interested in the application and development of analytical techniques such as gas chromatography, mass spectrometry, optical spectrometry and NMR. You have well developed social skills. You are a critical observer as well as a good analytical thinker. You are able to spot opportunities for improving existing processes and you are able to keep abreast with the state of the art in chemistry and gain knowledge of associated fields and disciplines. You can work in a team as well as independently. Further Information For this position SABIC is offering excellent primary and secondary working conditions. You have the opportunity to share your future in a growing international company in an ambitious, professional and dynamic environment. For further information, please contact: Kishan Gurram at SABIC T&I, tel +31611956447. Sharing our futures in leadership SABIC is one of the world’s leading manufacturers of chemicals, fertilizers, plastics and metals. We supply these materials to other companies, who use them to make products on which the world has come to depend. We are the largest and most reliably profitable public company in the Middle East. Our success is the result of our focus on three key areas: investment in local partnerships, outstanding research and technology programs, and an ambitious global growth strategy. And last, but certainly not least, because of our talented employees who have a passion to deliver. In Europe, SABIC employs over 6,000 professionals and is running 6 world-scale production sites and 4 technology & innovation centers. We are present in almost every European country. Major locations within our broad network of innovation, production and marketing are: Teesside (UK), Cartagena (Spain), Gelsenkirchen (Germany), Geleen (Netherlands) Bergen op Zoom (The Netherlands) and Genk (Belgium). Based upon this strong fundament, we are a key producer of olefins, polyolefins, engineering thermoplastics resins, films and sheets in Europe. At SABIC we are pushing the limits further. We are ambitious and striving to become the preferred world leader in chemicals. To achieve this ambition, we strongly invest in our most important asset – our employees. We see it as our task to help you develop a career with us that challenges you in ways that really make you come alive. Make your career happen with SABIC.

Section Head Erp Technical Support
Functional Business Analyst
Department SABIC IT SABIC ITs ambition is aligned with SABIC’s global ambition and supports the strategy by focus on growth, cost leadership and innovation. The SABIC organization is highly IT minded and considers IT as an opportunity to improve business processes and the way of working in this agile environment. SABIC IT wants to be a strategic partner within the transformation process of SABIC towards 2020. The department ERP Services Europe is responsible to provide user support for SABIC ERP deployed solutions within region Europe, to ensure excellent service delivery via incident, problem and change management. The Challenge The Section Head ERP Technical Support is responsible for implementing, maintaining and supporting the technical environment required by SAP and SAP related applications. The Section Head will lead the ERP Technical Support team in order to: Provide technical support for SABIC ERP deployed solutions to facilitate optimal operations within the services and the transform department. Secure un-interrupted supply of ERP solutions in order to guarantee the standards of operational excellence for the SABIC business processes. Provide technical support for multiple business units whose day to day operations are critically dependant on all ERP deployed solutions. Manage agreement (SLA) with our SAP hosting supplier. Secure availability of ERP systems. Your Profile Minimum education; University or Bachelor degree, preferably in IT or Engineering. Good understanding of company processes, goals and objectives and their metrics and measures; Leadership and people management skills; Excellent incident-, problem- and change management skills; Knowledge of financial planning and capital management concepts; In-depth knowledge of ITIL policies, procedures, systems and best practices in the diverse areas of IT; Excellent analytical and quantitative skills; Strong ability to remain focused on long-term objectives in light of immediate operational requirements; Able to participate in global multi-disciplinary & cultural teams and business relationships; Proven experience with SAP Basis. Further Information For more information about this role, please contact Leo Berghof, recruiter, tel +31(6) 24 6779 24. Sharing our futures in leadership SABIC is one of the world’s leading manufacturers of chemicals, fertilizers, plastics and metals. We supply these materials to other companies, who use them to make products on which the world has come to depend. We are the largest and most reliably profitable public company in the Middle East. Our success is the result of our focus on three key areas: investment in local partnerships, outstanding research and technology programs, and an ambitious global growth strategy. And last, but certainly not least, because of our talented employees who have a passion to deliver. In Europe, SABIC employs over 6,000 professionals and is running 6 world-scale production sites and 4 technology & innovation centers. We are present in almost every European country. Major locations within our broad network of innovation, production and marketing are: Teesside (UK), Cartagena (Spain), Gelsenkirchen (Germany), Geleen (Netherlands) Bergen op Zoom (The Netherlands) and Genk (Belgium). Based upon this strong fundament, we are a key producer of olefins, polyolefins, engineering thermoplastics resins, films and sheets in Europe. At SABIC we are pushing the limits further. We are ambitious and striving to become the preferred world leader in chemicals. To achieve this ambition, we strongly invest in our most important asset – our employees. We see it as our task to help you develop a career with us that challenges you in ways that really make you come alive. Make your career happen with SABIC.

Senior Scientist In Chemistry
Onderzoek wetenschap
Senior Scientist in chemistry Reference Number 1587 Location Sittard-Geleen Job Type Professional Vacancy Category Research & Development Department SABIC’s Technology and Innovation (T&I) netw...